HSE - PCRS

Application Details

HSE Application ID

HSE100077

HTA Number

25063

HTA Link

https://www.ncpe.ie/lonafarnib-zokinvy-hta-id-25063/

Drug

Lonafarnib

Brand

Zokinvy®

Applicant

Sentynl Therapeutics

Indication Applied For

Indicated for the treatment of patients 12 months of age and older with a genetically confirmed diagnosis of Hutchinson-Gilford Progeria syndrome or a processing-deficient progeroid laminopathy associated with either a heterozygous LMNA mutation with progerin-like protein accumulation or a homozygous or compound heterozygous ZMPSTE24 mutation.

Application Date

28/10/2025

Marketing Authorisation Date

18/07/2022

Application Status

Awaiting Proposal from Applicant

05/02/2026

Applicant Meeting Held with CPU

05/02/2026

Rapid Review Completed

27/11/2025

Rapid Review Commissioned

28/10/2025

Pricing and Reimbursement Application Complete

28/10/2025

New Search